Research Interest

  • Synthetic Methodology and Catalysis
  • Total Synthesis of Natural Products
  • Asymmetric Synthesis and photocatalysis
  • Development of Novel Antibiotics

  Academic Background

  • 2009-2014 : Ph.D., Department of Chemistry, Indian Institute of Technology Madras
  • 2007–2009 : M.Sc., School of Chemistry, Madurai Kamaraj University
  • 2004-2007 : B.Sc., Department of Chemistry, Periyar Arts College, Thiruvalluvar University

  Professional Experience

  • 2019–Present: Assistant Professor (Department of Chemistry, IIT-Bhilai)
  • 2018–2019 : Senior Research Investigator, Syngene International Ltd., Bangalore, India.
  • 2016-2017 : Post-Doctoral Research Associate, Department of Chemistry and Chemical Biology, Harvard University, Cambridge, USA
  • 2014-2016 : Post-Doctoral Research Associate, Institute of Organic and Bio-Organic Chemistry, University of Göttingen, Göttingen, Germany

  Awards and Fellowship

  • Prof. C. N. Pillai award for the best thesis in Ph.D., Organic Chemistry, IIT-Madras
  • CSIR- Senior Research Fellowship (April 2011), India
  • CSIR-Junior Research Fellowship (38th Rank, June-2011), India
  • CSIR-Junior Research Fellowship (June-2008), India.
  • Graduate Aptitude Test in Engineering (GATE, 45th Rank, March-2010), India


     Book Chapter

    • Sekar, G.; Karthikeyan, I.; Ganapathy, D. "Oxidation and Reduction Reactions in Domino Processes"; Domino Reactions: Concept for efficient Organic Synthesis." 2nd Edition, (L.F. Tietze, Ed.), ISBN 978-3-527-33432-2-Wiley-VCH, Weinheim.
     Selected Publications
    • Senthil Kumar, S.; Valdomir, G.; Ganapathy, D.; Zhang, Y.; Lutz F. Tietze. Enantioselective Total Synthesis of the Fungal Metabolite Blennolide D and the Enantiomers of Blennolide E and F. Org. Lett. 2018, 20, 2186–2189.
    • Valdomir, G.; Senthil Kumar, S.; Ganapathy, D.; Zhang, Y.; Lutz F. Tietze. Enantioselective Total Synthesis of Blennolide H and Phomopsis‐H76 A and Determination of Their Structure. Chem. Eur. J. 2018, 24, 8760-8763.
    • Senthil Kumar, S.; Valdomir, G.; Ganapathy, D.; zhangyun, Lutz F. Tietze. Enantioselective Total Synthesis of Chromanone Lactone Homo- and Heterodimers. Chem. Asian. J. 2018,13, 1888-18891.
    • Ganapathy, D.; Reiner, J. R.; Valdomir, G.; Senthil Kumar, S.; Lutz F. Tietze. Enantioselective Total Synthesis and Structure Confirmation of the Natural Dimeric Tetrahydroxanthenone Dicerandrol C. Chem. Eur. J.2017, 23,2290 –2302.
    • Tietze, L.F.; Jackenkroll, S.; Ganapathy, D.; Reiner, J. R. Tietze. Formal Synthesis of (–)-Siccanin Using an Enantioselective Domino Wacker/Carbonylation/Methoxylation Reaction. Synlett 2016, 27, 96-100.
    • Ganapathy, D.; Reiner, J. R.; Loeffler, L. E.; Ma, L.; Gnanaprakasam, B.; Niepoetter, B.; Koehne, I.; Lutz F. Tietze. Enantioselective Total Synthesis of Secalonic Acid E. Chem. Eur. J 2015, 21,16807 –16810.
    • Tietze, L.F.; Waldecker, B.; Ganapathy, D.; Eichhorst, C.; Lenzer, T.; Oum, K.; Reichmann, S. O.; Stalke, D. Four- and Sixfold Tandem-Domino Reactions Leading to Dimeric Tetrasubstituted Alkenes Suitable as Molecular Switches. Angew. Chem. Int. Ed. 2015, 54, 10317 –103210.
    • Ganapathy, D.; Sekar. G. Stable palladium nanoparticles catalyzed synthesis of benzonitriles using K4[Fe(CN)6]. Tetrahedron Lett. 2015, 2015, 56, 175-178.
    • Ganapathy, D.; Sekar. G. Efficient Synthesis of Polysubstituted Olefins Using Stable Palladium Nanocatalyst: Applications in Synthesis of Tamoxifen and Isocombretastatin A4. Tetrahedron Lett. 2015, 2015, 56, 175-178.
    • Sindhura, B.; Ganapathy, D.; Ankita, D.; Singh, R.; Sekar, G. FeCl2-BINAM complex catalyzed domino synthesis of bisindolylmethanes from indoles and primary alcohols. Synthesis 2014, 46, 0101–0109..
    • Ganapathy, D.; Sekar. G. Palladium nanoparticles stabilized by metal–carbon covalent bond: An efficient and reusable nanocatalyst in cross-coupling reactions. Catal. Commun. 2013, 39, 50-54..
    • Alamsetti, S. K.; Ganapathy, D.; Sekar, G. Enantioselective Oxidative Coupling of 2-Naphthol Derivatives by Copper-(R)-1,1'-Binaphthyl-2,2'-diamine-TEMPO Catalyst. Adv. Synth. Catal. 2013, 355, 2803-2808..
    • Thakur, K. G.; Ganapathy, D.; Sekar. G. D-Glucosamine as a green ligand for copper catalyzed synthesis of primary aryl amines from aryl halides and ammonia. Chem. Commun. 2011, 47, 5076–5078..
    • Naidu A. B. Ganapathy, D.; Sekar, G. Copper(I)-Catalyzed Intramolecular Caryl–O Bond-Forming Cyclization for the Synthesis of 1,4-Benzodioxines and Its Application in the Total Synthesis of Sweetening Isovanillins. Synthesis 2010, 20, 3509–3519.

Message From Director

IIT Bhilai is striving for research-driven undergraduate and postgraduate education. Our objective is to create an education system with multifacet outcomes including research, entrepreneurship, technical leadership, and above all, responsible citizenship. Read More


Subscribe to our Newsletter and stay tuned.