Dr. Ganapathy Dhandapani

Assistant Professor, 

Department of Chemistry, 

Indian Institute of Technology Bhilai

GEC Campus, Sejbahar, Raipur-492015, Chhattisgarh, India.  

E-mail: ganapathy@iitbhilai.ac.in

 

 RESEARCH INTEREST

Ø  Development of New Antibiotics for Multi-Drug Resistance Bacteria.

Ø  Total Synthesis of Natural Products.

Ø  Development of New Synthetic Methods in Organic Synthesis based on Metal Catalysis.

Ø  Excited State Transition Metal Photocatalysis.

PROFESSIONAL EXPERIENCE

Ø  2019 –Present :  Assistant Professor (Department of Chemistry, IIT-Bhilai).

Ø  2018 – 2019     :   Senior Research Investigator (Syngene International Ltd., Bangalore, India).

Ø  2016 - 2017 : Post-Doctoral Research Associate (Department of Chemistry and Chemical Biology, Harvard University, Cambridge, USA).

Ø  2014-2016        : Post-Doctoral Research Associate (Institute of Organic and Bio-Organic Chemistry, University of Göttingen, Göttingen, Germany).

ACADEMIC BACKGROUND

Ø  2009  - 2014    : Ph.D., Department of Chemistry, Indian Institute of Technology Madras.

Ø  2007 – 2009  :  M.Sc., School of Chemistry, Madurai Kamaraj University.

Ø  2004-2007     :  B.Sc., Department of Chemistry, Periyar Arts College, Thiruvalluvar University.

Courses

Ø  CY505 : Organic Reactions and Reagents (M.Sc., 2019 - Monsoon Semester).

Awards / Fellowships

Ø  Prof. C. N. Pillai award for the best thesis in Ph.D., Organic Chemistry, IIT-Madras.

Ø  CSIR- Senior Research Fellowship (April 2011), India.

Ø  CSIR-Junior Research Fellowship  (38th Rank, June-2011), India.

Ø   CSIR-Junior Research Fellowship (June-2008), India.

Ø  Graduate Aptitude Test in Engineering (GATE, 45th Rank, March-2010), India.

Book Chapter

"Oxidation and Reduction Reactions in Domino Processes"; Domino Reactions: Concept for efficient Organic Synthesis 2nd Edition, (L.F. Tietze, Ed.), ISBN 978-3-527-33432-2-Wiley-VCH, Weinheim. Sekar, G.; Karthikeyan, I.; Ganapathy, D.

 

List of Publications

1.      “Enantioselective Total Synthesis of the Fungal Metabolite Blennolide D and the Enantiomers of Blennolide E and F” Senthil Kumar, S.; Valdomir, G.; Ganapathy, D.; zhangyun, Lutz F. Tietze, Org. Lett., 2018, 20, 2186–2189.   

 

2.     “Enantioselective Total Synthesis of Blennolide H and Phomopsis‐H76 A and Determination of Their Structure” Valdomir, G.; Senthil Kumar, S.; Ganapathy, D.; Yun. Z; Lutz F. Tietze. Chem. Eur. J. 2018, 24, 8760-8763.

 

3.     “Enantioselective Total Synthesis of Chromanone Lactone Homo- and Heterodimers”” Senthil Kumar, S.; Valdomir, G.; Ganapathy, D.; zhangyun, Lutz F. Tietze. Chem. Asian. J. 2018, 13, 1888-18891.

 

4.     “Enantioselective Total Synthesis and Structure Confirmation of the Natural Dimeric Tetrahydroxanthenone Dicerandrol C” Ganapathy, D.; Reiner, J. R.; Valdomir, G.; Senthil Kumar, S.; Lutz F. Tietze. Chem. Eur. J. 2017, 23,2290 –2302.

 

  1. “Formal Synthesis of (–)-Siccanin Using an Enantioselective Domino Wacker/Carbonylation/Methoxylation Reaction” Tietze, L.F.; Jackenkroll, S.; Ganapathy, D.; Reiner, J. R. Synlett, 2016, 27, 96-100.

 

6.     “Enantioselective Total Synthesis of Secalonic Acid E” Ganapathy, D.; Reiner, J. R.; Loeffler, L. E.; Ma, L.; Gnanaprakasam, B.; Niepoetter, B.; Koehne, I.; Lutz F. Tietze. Chem. Eur. J. 2015, 21,16807 –16810.

 

7.     “Four- and Sixfold Tandem-Domino Reactions Leading to Dimeric Tetrasubstituted Alkenes Suitable as Molecular Switches” Tietze, L.F.; Waldecker, B.; Ganapathy, D.; Eichhorst, C.; Lenzer, T.; Oum, K.; Reichmann, S. O.; Stalke, D. Angew. Chem. Int. Ed. 2015, 54, 10317 –10321; Angew. Chem. 2015, 127, 10457 – 10461.

 

8.     “Stable palladium nanoparticles catalyzed synthesis of benzonitriles using K4[Fe(CN)6].” Ganapathy, D.; Sekar. G. Tetrahedron Lett., 2015, 56 (1), 175-178.

 

9.     “Efficient Synthesis of Polysubstituted Olefins Using Stable Palladium Nanocatalyst: Applications in Synthesis of Tamoxifen and Isocombretastatin A4.” Ganapathy, D.; Sekar. G. Org. Lett., 2014, 16, 3856–3859.

 

10.   “Palladium nanoparticles stabilized by metal–carbon covalent bond: An efficient and reusable nanocatalyst in cross-coupling reactions.” Ganapathy, D.; Sekar. G. Catal. Commun. 2013, 39, 50–54.

 

11.   “Enantioselective Oxidative Coupling of 2-Naphthol Derivatives by Copper-(R)-1,1'-Binaphthyl-2,2'-diamine-TEMPO Catalyst.” Alamsetti, S. K.; Ganapathy, D.; Sekar, G. Adv. Synth. Catal. 2013, 355, 2803-2808.

 

12.   “D-Glucosamine as a green ligand for copper catalyzed synthesis of primary aryl amines from aryl halides and ammonia.” Thakur, K. G.; Ganapathy, D.; Govindasamy Sekar.; Sekar. G. Chem. Commun., 2011, 47, 5076–5078.

 

13.   “Copper(I)-Catalyzed Intramolecular Caryl–O Bond-Forming Cyclization for the Synthesis of 1,4-Benzodioxines and Its Application in the Total Synthesis of Sweetening Isovanillins.” Naidu A. B. Ganapathy, D.; Sekar, G. Synthesis 2010, 20, 3509–3519.

 

14.   “FeCl2-BINAM complex catalyzed domino synthesis of bisindolylmethanes from indoles and primary alcohols.” Sindhura, B.; Ganapathy, D.; Ankita, D.; Singh, R.; Sekar, G. Synthesis 2014, 46, 0101–0109.

 

Patent
         “13-Membered Macrolides and uses Thereof” Carlsen, P.;
Ganapathy, D.; Myers, A.G.; (USA         patent, June 2017).

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