Research Interest

  • Synthetic Methodology and Catalysis
  • Total Synthesis of Natural Products
  • Asymmetric Synthesis and photocatalysis
  • Development of Novel Antibiotics

  Academic Background

  • 2009-2014 : Ph.D., Department of Chemistry, Indian Institute of Technology Madras
  • 2007–2009 : M.Sc., School of Chemistry, Madurai Kamaraj University
  • 2004-2007 : B.Sc., Department of Chemistry, Periyar Arts College, Thiruvalluvar University

  Professional Experience

  • 2019–Present: Assistant Professor (Department of Chemistry, IIT-Bhilai)
  • 2018–2019 : Senior Research Investigator, Syngene International Ltd., Bangalore, India.
  • 2016-2017 : Post-Doctoral Research Associate, Department of Chemistry and Chemical Biology, Harvard University, Cambridge, USA
  • 2014-2016 : Post-Doctoral Research Associate, Institute of Organic and Bio-Organic Chemistry, University of Göttingen, Göttingen, Germany

  Awards and Fellowship

  • Prof. C. N. Pillai award for the best thesis in Ph.D., Organic Chemistry, IIT-Madras
  • CSIR- Senior Research Fellowship (April 2011), India
  • CSIR-Junior Research Fellowship (38th Rank, June-2011), India
  • CSIR-Junior Research Fellowship (June-2008), India.
  • Graduate Aptitude Test in Engineering (GATE, 45th Rank, March-2010), India

 Publications

     Book Chapter

    • Sekar, G.; Karthikeyan, I.; Ganapathy, D. "Oxidation and Reduction Reactions in Domino Processes"; Domino Reactions: Concept for efficient Organic Synthesis." 2nd Edition, (L.F. Tietze, Ed.), ISBN 978-3-527-33432-2-Wiley-VCH, Weinheim.
     Selected Publications
    • Senthil Kumar, S.; Valdomir, G.; Ganapathy, D.; Zhang, Y.; Lutz F. Tietze. Enantioselective Total Synthesis of the Fungal Metabolite Blennolide D and the Enantiomers of Blennolide E and F. Org. Lett. 2018, 20, 2186–2189.
    • Valdomir, G.; Senthil Kumar, S.; Ganapathy, D.; Zhang, Y.; Lutz F. Tietze. Enantioselective Total Synthesis of Blennolide H and Phomopsis‐H76 A and Determination of Their Structure. Chem. Eur. J. 2018, 24, 8760-8763.
    • Senthil Kumar, S.; Valdomir, G.; Ganapathy, D.; zhangyun, Lutz F. Tietze. Enantioselective Total Synthesis of Chromanone Lactone Homo- and Heterodimers. Chem. Asian. J. 2018,13, 1888-18891.
    • Ganapathy, D.; Reiner, J. R.; Valdomir, G.; Senthil Kumar, S.; Lutz F. Tietze. Enantioselective Total Synthesis and Structure Confirmation of the Natural Dimeric Tetrahydroxanthenone Dicerandrol C. Chem. Eur. J.2017, 23,2290 –2302.
    • Tietze, L.F.; Jackenkroll, S.; Ganapathy, D.; Reiner, J. R. Tietze. Formal Synthesis of (–)-Siccanin Using an Enantioselective Domino Wacker/Carbonylation/Methoxylation Reaction. Synlett 2016, 27, 96-100.
    • Ganapathy, D.; Reiner, J. R.; Loeffler, L. E.; Ma, L.; Gnanaprakasam, B.; Niepoetter, B.; Koehne, I.; Lutz F. Tietze. Enantioselective Total Synthesis of Secalonic Acid E. Chem. Eur. J 2015, 21,16807 –16810.
    • Tietze, L.F.; Waldecker, B.; Ganapathy, D.; Eichhorst, C.; Lenzer, T.; Oum, K.; Reichmann, S. O.; Stalke, D. Four- and Sixfold Tandem-Domino Reactions Leading to Dimeric Tetrasubstituted Alkenes Suitable as Molecular Switches. Angew. Chem. Int. Ed. 2015, 54, 10317 –103210.
    • Ganapathy, D.; Sekar. G. Stable palladium nanoparticles catalyzed synthesis of benzonitriles using K4[Fe(CN)6]. Tetrahedron Lett. 2015, 2015, 56, 175-178.
    • Ganapathy, D.; Sekar. G. Efficient Synthesis of Polysubstituted Olefins Using Stable Palladium Nanocatalyst: Applications in Synthesis of Tamoxifen and Isocombretastatin A4. Tetrahedron Lett. 2015, 2015, 56, 175-178.
    • Sindhura, B.; Ganapathy, D.; Ankita, D.; Singh, R.; Sekar, G. FeCl2-BINAM complex catalyzed domino synthesis of bisindolylmethanes from indoles and primary alcohols. Synthesis 2014, 46, 0101–0109..
    • Ganapathy, D.; Sekar. G. Palladium nanoparticles stabilized by metal–carbon covalent bond: An efficient and reusable nanocatalyst in cross-coupling reactions. Catal. Commun. 2013, 39, 50-54..
    • Alamsetti, S. K.; Ganapathy, D.; Sekar, G. Enantioselective Oxidative Coupling of 2-Naphthol Derivatives by Copper-(R)-1,1'-Binaphthyl-2,2'-diamine-TEMPO Catalyst. Adv. Synth. Catal. 2013, 355, 2803-2808..
    • Thakur, K. G.; Ganapathy, D.; Sekar. G. D-Glucosamine as a green ligand for copper catalyzed synthesis of primary aryl amines from aryl halides and ammonia. Chem. Commun. 2011, 47, 5076–5078..
    • Naidu A. B. Ganapathy, D.; Sekar, G. Copper(I)-Catalyzed Intramolecular Caryl–O Bond-Forming Cyclization for the Synthesis of 1,4-Benzodioxines and Its Application in the Total Synthesis of Sweetening Isovanillins. Synthesis 2010, 20, 3509–3519.

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